Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Article Title: Cost-Effectiveness of Alternative Surveillance Strategies for Hepatocellular Carcinoma in Patients with Cirrhosis
doi: 10.1016/j.cgh.2008.08.005
Figure Lengend Snippet: Simplified schematic of Markov health states. In each cycle, individuals may remain in the same health state, transition to the following state, or die from liver disease or unrelated causes. For example, transition 1 reflects cancer incidence; transition 2 is determined by the sensitivity of the surveillance modality; and transition 3 is the proportion of treatment-eligible tumors. Best available data were used to determine transitions. The grey boxes represent the possible benefit of surveillance: detection and treatment of small HCC.
Article Snippet: We developed a computer-based Markov model (TreeAge Pro software 2005) to simulate disease progression, surveillance, diagnosis, and treatment of HCC in a cohort of patients with compensated cirrhosis.
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